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         Interstitial
            Cystitis 
        Interstitial cystitis is described by doctors as a disease
          of unknown aetiology. This is medical speak for we have no idea why
          it is caused. Cystitis in general just means inflammation of the bladder.
          This is of course most commonly caused by infection but any irritant
          can cause cystitis. In interstitial cystitis the cause of irritation
          is unknown. 
        What
                are the symptoms? 
        Interstitial cystitis is most commonly manifest by by
          an increasing discomfort over the lower abdomen as the bladder fills.
          This usually improves after voiding. Patients find that they pass water
          more frequently than normal to try to avoid the pain. Research on the
          causes continues with many possible explanations being explored. None
          are yet proven. 
        What tests are needed? 
        Many patients have such classical symptoms that special
          tests are not necessarily needed, most patients however will undergo
          a bladder check and biopsy. This will look for evidence of the changes
          of interstitial cystitis. Prominent bleeding vessels in the bladder
          after a bladder stretch, bladder ulcers and a special type of inflammatory
          cell within the wall of the bladder. 
        What is the treatment? 
        Normal bladders produce a chemical called GAG or glycose
          amino glycans. This forms a non stick type layer in the bladder which
          resists the noxious chemicals that are usually found in the urine.
          Most treatments centre on trying to bolster this non stick layer. Various
          oral medications and bladder washes are available for this purpose.
          Normally your doctor will work through the possible treatments after
          making a diagnosis. 
        What is the outlook? 
        Interstitial cystitis comes and goes. It is however a
          lifelong disease, the treatments that the patient is given are to improve
          the symptoms during flare ups of the disease, in between times treatment
          is often not needed. 
          
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